Selling price $ 132.00
Product No. ES002-A
Formula C18H18O2
MW 266.33
CAS# 528-43-8
Synonym Kopnolia; 2,2'-Bichavicol
Natural Source Magnoliae Cortex
Chemical Family Lignan
Appearance Brown Powder
Purity ≥95%
Storage +4℃
NMR Download
HPLC Download
MS Download
Manufacturer Ensol Biosciences Inc.
Origin of Country Made in Korea
  • Anti-inflammatory and analgesic effects.
  • Magnolol protect rat heart mitochondria against lipid peroxidation.
  • Magnolol inhibits collagen-induced platelet serotonin release.
  • Antimicrobial activity against periodontopathic microorganisms.
  • Magnolol decreases body temperature by reducing 5-hydroxytryptamine release in the rat hypothalamus.
  • Magnolol protects cortical neuronal cells from chemical hypoxia in rats.
  • Magnolol attenuates peroxidative damage and improves survival of rats with sepsis.
  • Antifungal activity.
  • Intravenous pretreatment with magnolol protects myocardium against stunning.
  • Antimicrobial activity.
  • Magnolol reduces myocardial ischemia/reperfusion injury via neutrophil inhibition in rats.
  • Magnolol suppresses proliferation of cultured human colon and liver cancer cells by inhibiting DNA synthesis and activating apoptosis.
  • Protective effect on the small intestinal ischemia-reperfusion injury.
  • Magnolol induces apoptosis in human leukemia cells via cytochrome c release and caspase activation.
  • Magnolol protects against cerebral ischaemic injury of rat heatstroke.
  • Inhibitory effect on tumour metastasis in mice.
  • In vitro antibacterial and anti-inflammatory effects against Propionibacterium sp.
  • Magnolol and honokiol enhance HL-60 human leukemia cell differentiation induced by 1,25-dihydroxyvitamin D3 and retinoic acid.
  • Magnolol stimulates lipolysis in lipid-laden RAW 264.7 macrophages.
  • Neurotrophic effect of magnolol in the hippocampal CA1 region of senescence-accelerated mice (SAMP1).
  • Neuroprotective activity of honokiol and magnolol in cerebellar granule cell damage.
  • In vitro anti-mutagenic effect against direct and indirect mutagens.
  • Protective effects against oxidized LDL-induced apoptosis in endothelial cells.
  • Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.
  • Protective effect on TBHP-induced injury in H460 cells partially via a p53 dependent mechanism.
  • Anti-clastogenic effect on benzo(a)pyrene-induced clastogenicity in mice.
  • Magnolol enhances pentobarbital-induced sleeping behaviors: possible involvement of GABAergic systems.
  • The protective efficacy in hind limb ischemia-reperfusion injury.
  • Protective effect against hydrogen peroxide-induced oxidative stress in human lens epithelial cells.
  • Antinociceptive actions on glutamatergic and inflammatory pain.
  • Inhibitory effect on TPA-induced skin inflammation and tumor promotion in mice.
  • Anticancer potential for lung cancer treatment.
  • Magnolol attenuates the lung injury in hypertonic saline treatment from mesenteric ischemia reperfusion through diminishing iNOS.
  • Magnolol protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity through activation of mitochondrial function.
  • Anti-arthritic effects in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.
  • Magnolol protects against MPTP/MPP(+)-induced toxicity via inhibition of oxidative stress in In vivo and In vitro models of Parkinson's disease.
  • Cardiovascular protection.
  • Protective effect on lipopolysaccharide-induced acute lung injury in mice.
  • Magnolol protects against oxidative stress-mediated neural cell damage by modulating mitochondrial dysfunction and PI3K/Akt signaling.
  • Magnolol ameliorates ligature-induced periodontitis in rats and osteoclastogenesis: in vivo and in vitro study.
  • Resuscitation from experimental traumatic brain injury by magnolol therapy.
  • Antidiabetic and hepatoprotective effects on diabetic rats induced by high-fat diet and streptozotocin.
  • Magnolol reduces UVB-induced photodamage by regulating matrix metalloproteinase activity.
  • Magnolol inhibits growth of gallbladder cancer cells through the p53 pathway.
  • Magnolol reduces bleomycin-induced rodent lung fibrosis.
  • Magnolol and honokiol exert a synergistic anti-tumor effect through autophagy and apoptosis in human glioblastomas.
Biological activity References (PubMed) Shipping/Exchange/Return


  • (For South Korea) Free delivery service is available in all products. Shipping takes 1-3 business days.

  • (For any country in the world except South Korea) The fixed delivery charge is 25USD when the total value of your order exceeds 250USD/EUR. Shipping takes 7-14 business days. Orders are shipped directly to your company or institute.


  • If out products have any problems and are not satisfied with your purchase, you may exchange or return the items at anytime within 14 days from the delivery date. Please see the following instructions when you return products.

  • Please let us know the purchase order number or package tracking number (by E-mail,

  • Return shipping is absolutely FREE.

  • This offer is only valid for products purchased directly from Ensol Biosciences.

  • Once your return request is received, your refund will be processed and a credit will be automatically applied to your credit card or original method of payment within 7 days. Please note that depending on your credit card company, it may take additional 2-10 business days after your credit is applied for it to post to your account.

  • All requests for returns should have prior notice and the items should be shipped back to Ensol Biosciences in the original package and the same condition.

Privacy policy/ Use Agreement/ Contact Us/ Buying Guide/ Shipping, Exchange, Return

Company : Ensol Biosciences Inc. | CEO : Hae-Jin Kim | Business Number : 314-81-39908

Headquarter : (34036) 51, Techno 10-ro, Yuseong-gu, Daejeon, Korea | TEL : 042-939-4500 / 4545

Copyright 2016. Ensol Biosciences Inc.