Selling price $ 187.00
Product No. ES056-A
Formula C20H20O7
MW 372.37
CAS# 481-53-8
Synonym Ponkanetin; Pentamethoxyflavone; 4',5,6,7,8-Pentamethoxyflavone
Natural Source Citri Unshii Pericarpium
Chemical Family Flavone
Appearance Yellow Powder
Purity ≥95%
Storage +4℃
NMR Download
HPLC Download
MS Download
Manufacturer Ensol Biosciences Inc.
Origin of Country Made in Korea
  • Inhibition of invasion of MO4 mouse cells into embryonic chick heart in vitro.
  • Inhibition of leukaemic HL-60 cell growth.
  • Tissue distribution and neuroprotective effects in a rat model of Parkinson's disease.
  • Induction of cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells.
  • Inhibition of growth of human mammary cancer cells and cytolysis by natural killer cells.
  • Suppression of IL-1beta-induced cyclooxygenase (COX)-2 expression through inhibition of p38 MAPK, JNK, and AKT activation in human lung carcinoma cells.
  • Induction of G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells.
  • Sensitization of cisplatin-resistant human ovarian cancer cells through downregulation of phosphoinositide 3-kinase/Akt signaling pathway.
  • Inhibition of PGDF-BB-induced proliferation and migration of aortic smooth muscle cells by blocking AKT activation.
  • Increase of glucose uptake in murine adipocytes.
  • Anti-neuroinflammatory effects via NF-κB modulation in lipopolysaccharide-stimulated microglial cells.
  • Induction of apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways.
  • Antitumor efficacy by targeting the oxidative stress mediated on 7,12-dimethylbenz(a) anthracene-induced proliferative breast cancer in Sprague-Dawley rats.
Biological activity References (PubMed) Shipping/Exchange/Return


  • (For South Korea) Free delivery service is available in all products. Shipping takes 1-3 business days.

  • (For any country in the world except South Korea) The fixed delivery charge is 25USD when the total value of your order exceeds 250USD/EUR. Shipping takes 7-14 business days. Orders are shipped directly to your company or institute.


  • If out products have any problems and are not satisfied with your purchase, you may exchange or return the items at anytime within 14 days from the delivery date. Please see the following instructions when you return products.

  • Please let us know the purchase order number or package tracking number (by E-mail,

  • Return shipping is absolutely FREE.

  • This offer is only valid for products purchased directly from Ensol Biosciences.

  • Once your return request is received, your refund will be processed and a credit will be automatically applied to your credit card or original method of payment within 7 days. Please note that depending on your credit card company, it may take additional 2-10 business days after your credit is applied for it to post to your account.

  • All requests for returns should have prior notice and the items should be shipped back to Ensol Biosciences in the original package and the same condition.

Privacy policy/ Use Agreement/ Contact Us/ Buying Guide/ Shipping, Exchange, Return

Company : Ensol Biosciences Inc. | CEO : Hae-Jin Kim | Business Number : 314-81-39908

Headquarter : (34036) 51, Techno 10-ro, Yuseong-gu, Daejeon, Korea | TEL : 042-939-4500 / 4545

Copyright 2016. Ensol Biosciences Inc.